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BMJ Case Rep ; 13(9)2020 Sep 14.
Article in English | MEDLINE | ID: covidwho-767824

ABSTRACT

We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis. Both conditions induce a proinflammatory cytokine drive resulting, among others, in a prothrombotic state. The disruption of the coagulation system in this case was supported by elevated D-dimers, fibrinogen and ferritin levels, consistent with thrombotic complications reported in some adult patients infected with COVID-19. The child also exhibited prolonged viral shedding that suggests severe disease.


Subject(s)
Coronavirus Infections/complications , Intracranial Thrombosis/microbiology , Pneumonia, Viral/complications , Tuberculosis, Meningeal/complications , Venous Thrombosis/microbiology , COVID-19 , Child, Preschool , Coinfection , Female , Humans , Pandemics , Severity of Illness Index
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